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How Food Intake Modifies the Gut

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With more than 10% of the world’s population obese and 40% overweight, obesity constitutes one of the most crucial health challenges. However, existing therapeutic options remain scarce and poorly efficient. Few years ago, scientists from the University of Geneva (UNIGE), Switzerland, discovered that the absorptive surface and function of the gut change due to certain external stimuli, such as exposure to cold. Today, by using different mouse models combined with human intestinal biopsies, they decipher the molecular mechanisms that govern this surprising organ plasticity, and uncover that increasing the food amount elevates the intestinal absorptive surface and function. Mechanistically, this is due to the enhanced expression of PPARα, a regulating protein necessary for the overeating-induced increase in the capacity of the gut to absorb calories. Furthermore, if high amounts of food increase the gut absorptive surface, food restriction can reverse the process and return it close to normal. This phenomenon could be reproduced using pharmacological and genetic approaches, thereby suggesting potential avenues to limit obesity. These results are published in the journal Nature Communications.

Source: medicalxpress.com

Health Care

Few Patients Aware If Their Doctor Took Gifts From Drug Companies, Study Shows

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PHILADELPHIA — Would it surprise you to learn your physician accepts a gift from a pharmaceutical company? If so, you’re in the majority. A 2017 study finds that most Americans have received care from a doctor who received some type of payment from a drug maker — and very few patients knew. Researchers at Drexel…

The post Few patients aware if their doctor took gifts from drug companies, study shows appeared first on Study Finds.

Source Here: studyfinds.org

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Videocast: Wind Chill Advisory for Tuesday Night

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Winds will make it feel like between 20 to 30 degrees below zero.

Original Source: wisn.com

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How to Perform CPR During COVID Pandemic: AHA Updates Guidelines

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DALLAS, Texas — Performing CPR can be a split-second decision that saves a life, but are people becoming more fearful of giving first aid during the coronavirus pandemic? A new report by researchers with the American Heart Association is unveiling updated CPR guidelines which take into account COVID-19’s more contagious variants like Delta and Omicron. With…

The post How to perform CPR during COVID pandemic: AHA updates guidelines appeared first on Study Finds.

Article: studyfinds.org

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