Connect with us

Health Care

How Food Intake Modifies the Gut

Grant

Published

on

With more than 10% of the world’s population obese and 40% overweight, obesity constitutes one of the most crucial health challenges. However, existing therapeutic options remain scarce and poorly efficient. Few years ago, scientists from the University of Geneva (UNIGE), Switzerland, discovered that the absorptive surface and function of the gut change due to certain external stimuli, such as exposure to cold. Today, by using different mouse models combined with human intestinal biopsies, they decipher the molecular mechanisms that govern this surprising organ plasticity, and uncover that increasing the food amount elevates the intestinal absorptive surface and function. Mechanistically, this is due to the enhanced expression of PPARα, a regulating protein necessary for the overeating-induced increase in the capacity of the gut to absorb calories. Furthermore, if high amounts of food increase the gut absorptive surface, food restriction can reverse the process and return it close to normal. This phenomenon could be reproduced using pharmacological and genetic approaches, thereby suggesting potential avenues to limit obesity. These results are published in the journal Nature Communications.

Source: medicalxpress.com

Health Care

Scientists Discover Antibodies That Induce Broad Immunity Against SARS Viruses, Including Emerging Variants

Grant

Published

on

By

As the world has witnessed firsthand, SARS-CoV-2, the virus that causes COVID, is difficult to control because of its ability to rapidly mutate and produce many different variants. Scientists at Scripps Research have now identified antibodies that are effective against many different SARS-CoV-2 variants, as well as other SARS viruses like SARS-CoV-1, the highly lethal virus that caused an outbreak in 2003. The results showed that certain animals are surprisingly more able to make these types of “pan-SARS virus” antibodies than humans, giving scientists clues as to how to make better vaccines.

Continue Reading

Health Care

New Drug Eliminates Over 300 Kinds of Antibiotic-resistant Bacteria

Grant

Published

on

URBANA-CHAMPAIGN, Ill. — For patients with a urinary tract infection, what’s the best way to deal with it? You can go to your doctor for antibiotics, but you run the risk of the medication not working the next time around. If you wait it out, you may have to deal with agonizing symptoms for days.…

The post New drug eliminates over 300 kinds of antibiotic-resistant bacteria appeared first on Study Finds.

Original Post: studyfinds.org

Continue Reading

Health Care

Monkeypox Vaccine Availability and Effectiveness

Grant

Published

on

By

A smallpox vaccine shown to protect against monkeypox has come under huge global demand, leading health authorities to warn against repeating the unequal distribution seen during the COVID pandemic.

Continue Reading

Trending

Chimed.com